Our Products
We offer a selection of liver-derived products for drug metabolism-related research, mainly cryopreserved hepatocytes from human and toxicologically-relevant species i.e. monkey, minipig, dog, rat and mouse. We can also provide subcellular liver fractions upon request.
Cryopreserved Hepatocytes
An inventory of hepatocytes is available upon request, a CoA for each lot specifies qualification, such as short- or long-term as sandwich or as 3D-spheroid culture, biliary canaliculi formation, metabolic phase I and II drug metabolizing enzyme activity, response to specific inducers…
Advantages of using KaLy-Cell’s products:
All preparations are made and characterized according to Standard Operating Procedures.
Quality is governed by the assigned Product Study Director and KaLy-Cell’s Quality Assurance.
Our commitment to ethics
KaLy-Cell fully supports the ethical use of human and animal tissues and believes that in order to maintain public confidence and trust, all tissue used must be obtained ethically and with appropriate consent, and be handled and used sensitively and responsibly by researchers. We receive human tissue donations from two major sources: non-transplantable tissues from heart-beating donors (Agreement of the French Agency of Biomedicine, CSP article L 1232-3), and tissue which is removed during surgical operations and would otherwise be discarded as biological waste. KaLy-Cell is authorized by the French Ministry of Research to prepare and store products from human origin for in vitro research and service purposes, to distribute and export to academia and industry human samples for in vitro studies (CSP articles L 1243-3, L 1243-4 and L 1245-5). KaLy-Cell is authorized by the Department for Protection of Populations to manipulate tissues and cells of animal origin.
Safety, Handling and Storage
The products are distributed for research purposes only. They have not been approved for therapeutic or diagnostic purposes. Cryopreserved Hepatocytes should be stored in liquid nitrogen vapor (-150°C or colder). They should be thawed in accordance with our thawing protocol, which is provided with hepatocytes.